|
|
Registros recuperados : 217 | |
2. | | MOREIRA, R.; BRIGHENTI, C.; PANETTO, J. C. do C.; RESENDE, J. C. de. Método Bayesiano no ajuste do modelo de Wood para curva de lactação do gado Gir. Revista da Estatística da Universidade Federal de Ouro Preto, v. 3, n. 3, p. 531-535, 2014. Edição dos resumos expandidos da 59a Reunião Anual da Regional Brasileira da Sociedade Internacional de Biometria, 2014, Ouro Preto. Biblioteca(s): Embrapa Gado de Leite. |
| |
5. | | SILVA, M. V. G. B.; MACHADO, M. A.; PANETTO, J. C. do C.; MARTINS, M. F. Inovações nos programas de melhoramento de bovinos de leite com foco em genômica. In: VILELA, D.; FERREIRA, R. de P.; FERNANDES, E. N.; JUNTOLLI, F. V. (Ed.). Pecuária de leite no Brasil: cenários e avanços tecnológicos. Brasília, DF: Embrapa, 2016. p. 345-357. Biblioteca(s): Embrapa Gado de Leite. |
| |
9. | | SILVA, M. V. G. B.; VERARDO, L. L.; MACHADO, M. A.; PANETTO, J. C. do C.; CAROLINO, I.; CAROLINO, N. Candidate genes for disease, reproduction and meat quality traits in Portuguese native breeds. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 12., 2022, Rotterdam. Proceedings... Rotterdam: [s.n.], 2022. Biblioteca(s): Embrapa Gado de Leite. |
| |
11. | | CARVALHO, N. S.; DALTRO, D. S.; MACHADO, J. D.; CAMARGO, E. V.; PANETTO, J. C. do C.; COBUCI, J. A. Genetic parameters and genetic trends of conformation and management traits in Dairy Gir cattle. Arquivo Brasileiro de Medicina Veterinária e Zootecnia, v. 73, n. 4, p. 938-948, 2021. Biblioteca(s): Embrapa Gado de Leite. |
| |
12. | | PACHECO, G. B.; NASCIMENTO, G. C.; PINHEIRO, R.; TEIXEIRA, R. B.; VERNEQUE, R. da S.; PANETTO, J. C. do C. Genetic parameters of milk production in gyr dairy cattle (Bos indicus). In: SIMPÓSIO NACIONAL DE BOVINOCULTURA LEITEIRA - SIMLEITE, 5.; SIMPÓSIO INTERNACIONAL DE BOVINOCULTURA LEITEIRA, 3., 2015, Viçosa, MG. Anais... Viçosa: UFV, 2015. p. 365-368 Biblioteca(s): Embrapa Gado de Leite. |
| |
13. | | VERNEQUE, R. da S.; VERONEZE, R.; PANETTO, J. C. do C.; SILVA, M. V. G. B.; TORAL, F. L. B. A contribuição do melhoramento animal para a pecuária de leite. In: VILELA, D.; FERREIRA, R. de P.; FERNANDES, E. N.; JUNTOLLI, F. V. (Ed.). Pecuária de leite no Brasil: cenários e avanços tecnológicos. Brasília, DF: Embrapa, 2016. p. 255-264. Biblioteca(s): Embrapa Gado de Leite. |
| |
15. | | BRION, C. T.; SANTOS, L. B.; REIS, D. R. de L.; MARTINS, M. F.; SILVA, M. V. G. B.; PANETTO, J. C. do C.; MACHADO, M. A. Banco de DNA de Bovinos: avaliação de metodologias alternativas para extração de DNA. In: WORKSHOP DE INICIAÇÃO CIENTÍFICA DA EMBRAPA GADO DE LEITE, 16., 2015, Juiz de Fora, MG Anais... Juiz de Fora: Embrapa Gado de Leite, 2015. 1 CD-ROM. (Embrapa Gado de Leite. Documentos, 185.). 2 p. Biblioteca(s): Embrapa Gado de Leite. |
| |
16. | | BUZANSKAS, M. E.; CHUD, T. C. S.; PANETTO, J. C. do C.; MACHADO, M. A.; SILVA, L. O. C. da; SILVA, M. V. G. B.; MUNARI, D. P. Breeding structure and genetic variability in nelore and gyr breeds from brazil na índia. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 55.; CONGRESSO BRASILEIRO DE ZOOTECNIA, 28., 2018, Goiânia. Construindo saberes, formando pessoas e transformando a produção animal: anais eletrônicos. Goiânia: Sociedade Brasileira de Zootecnia, 2018. Biblioteca(s): Embrapa Gado de Leite. |
| |
18. | | SANTOS, D. J. A.; PEIXOTO, M. G. C. D.; BORQUIS, R. R. A.; VERNEQUE, R. da S.; PANETTO, J. C. do C.; TONHATI, H. Comparison of random regression models to estimate genetic parameters for milk production in guzerat (Bos indicus) cows. Genetics and Molecular Research, v. 12, n. 1, p. 143-153, 2013. Biblioteca(s): Embrapa Gado de Leite. |
| |
19. | | PANETTO, J. C. do C.; VAL, J. C.; MARCONDES, C. R.; PEIXOTO, M. G. C. D.; VERNEQUE, R. da S.; FERRAZ, B. S.; GOLDEN, B. L. Female fertility in a Guzerat dairy herd: Heterogeneity of variance components for calving intervals. Journal Animal Science, v. 89, (E-Suppl. 1); Journal of Dairy Science, v. 94, (E-Suppl. 1), p.25, 2011 Biblioteca(s): Embrapa Pecuária Sudeste. |
| |
20. | | PERIPOLLI, E.; TONUSSI, R. L; VERNEQUE, R. Da S.; PANETTO, J. C. do C.; MACHADO, M. A.; SILVA, M. V. G. B.; BALDI, F. Exploring runs of homozygosity patterns in Gyr cattle. In: INTERNATIONAL MEETING OF ADVANCES IN ANIMAL SCIENCE, 1, 2016, Jaboticabal. Anais ... Jaboticabal: [s.n.], 2016. Biblioteca(s): Embrapa Gado de Leite. |
| |
Registros recuperados : 217 | |
|
|
Registro Completo
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
10/02/2023 |
Data da última atualização: |
14/06/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
PERIPOLLI, E.; STAFUZZA, N. B.; MACHADO, M. A.; PANETTO, J. C. do C.; EGITO, A. A. do; BALDI, F.; SILVA, M. V. G. B. |
Afiliação: |
ELISA PERIPOLLI, Universidade Estadual Paulista; NEDENIA BONVINO STAFUZZA, Centro de Pesquisa em Bovinos de Corte; MARCO ANTONIO MACHADO, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; ANDREA ALVES DO EGITO, CNPGC; FERNANDO BALDI, Universidade Estadual Paulista; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL. |
Título: |
Assessment of copy number variants in three Brazilian locally adapted cattle breeds using whole-genome re-sequencing data. |
Ano de publicação: |
2023 |
Fonte/Imprenta: |
Animal Genetics, v. 54, n. 3, p. 254-270, 2023. |
DOI: |
https://doi.org/10.1111/age.13298 |
Idioma: |
Inglês |
Conteúdo: |
Further characterization of genetic structural variations should strongly focus on small and endangered local breeds given their role in unraveling genes and structural variants underlying selective pressures and phenotype variation. A comprehensive genome-wide assessment of copy number variations (CNVs) based on whole-genome re-sequencing data was performed on three Brazilian locally adapted cattle breeds (Caracu Caldeano, Crioulo Lageano, and Pantaneiro) using the ARS-UCD1.2 genome assembly. Data from 36 individuals with an average coverage depth of 14.07× per individual was used. A total of 24?945 CNVs were identified distributed among the breeds (Caracu Caldeano = 7285, Crioulo Lageano = 7297, and Pantaneiro = 10 363). Deletion events were 1.75?2.07-fold higher than duplications, and the total length of CNVs is composed mostly of a high number of segments between 10 and 30?kb. CNV regions (CNVRs) are not uniformly scattered throughout the genomes (n = 463), and 105 CNVRs were found overlapping among the studied breeds. Functional annotation of the CNVRs revealed variants with high consequence on protein sequence harboring relevant genes, in which we highlighted the BOLA-DQB, BOLA-DQA5, CD1A, ?-defensins, PRG3, and ULBP21 genes. Enrichment analysis based on the gene list retrieved from the CNVRs disclosed over-represented terms (p?0.01) strongly associated with immunity and cattle resilience to harsh environments. Additionally, QTL associated with body conformation and dairy-related traits were also unveiled within the CNVRs. These results provide better understanding of the selective forces shaping the genome of such cattle breeds and identify traces of natural selection pressures by which these populations have been exposed to challenging environmental conditions. MenosFurther characterization of genetic structural variations should strongly focus on small and endangered local breeds given their role in unraveling genes and structural variants underlying selective pressures and phenotype variation. A comprehensive genome-wide assessment of copy number variations (CNVs) based on whole-genome re-sequencing data was performed on three Brazilian locally adapted cattle breeds (Caracu Caldeano, Crioulo Lageano, and Pantaneiro) using the ARS-UCD1.2 genome assembly. Data from 36 individuals with an average coverage depth of 14.07× per individual was used. A total of 24?945 CNVs were identified distributed among the breeds (Caracu Caldeano = 7285, Crioulo Lageano = 7297, and Pantaneiro = 10 363). Deletion events were 1.75?2.07-fold higher than duplications, and the total length of CNVs is composed mostly of a high number of segments between 10 and 30?kb. CNV regions (CNVRs) are not uniformly scattered throughout the genomes (n = 463), and 105 CNVRs were found overlapping among the studied breeds. Functional annotation of the CNVRs revealed variants with high consequence on protein sequence harboring relevant genes, in which we highlighted the BOLA-DQB, BOLA-DQA5, CD1A, ?-defensins, PRG3, and ULBP21 genes. Enrichment analysis based on the gene list retrieved from the CNVRs disclosed over-represented terms (p?0.01) strongly associated with immunity and cattle resilience to harsh environments. Additionally, QTL associated with body conformation and ... Mostrar Tudo |
Palavras-Chave: |
Variação fenotípica. |
Thesagro: |
Bovino; Gado Crioulo; Genoma; Raça. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1151656/1/Assessment-of-copy-number-variants-in-three-Brazilian.pdf
|
Marc: |
LEADER 02604naa a2200265 a 4500 001 2151656 005 2023-06-14 008 2023 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1111/age.13298$2DOI 100 1 $aPERIPOLLI, E. 245 $aAssessment of copy number variants in three Brazilian locally adapted cattle breeds using whole-genome re-sequencing data.$h[electronic resource] 260 $c2023 520 $aFurther characterization of genetic structural variations should strongly focus on small and endangered local breeds given their role in unraveling genes and structural variants underlying selective pressures and phenotype variation. A comprehensive genome-wide assessment of copy number variations (CNVs) based on whole-genome re-sequencing data was performed on three Brazilian locally adapted cattle breeds (Caracu Caldeano, Crioulo Lageano, and Pantaneiro) using the ARS-UCD1.2 genome assembly. Data from 36 individuals with an average coverage depth of 14.07× per individual was used. A total of 24?945 CNVs were identified distributed among the breeds (Caracu Caldeano = 7285, Crioulo Lageano = 7297, and Pantaneiro = 10 363). Deletion events were 1.75?2.07-fold higher than duplications, and the total length of CNVs is composed mostly of a high number of segments between 10 and 30?kb. CNV regions (CNVRs) are not uniformly scattered throughout the genomes (n = 463), and 105 CNVRs were found overlapping among the studied breeds. Functional annotation of the CNVRs revealed variants with high consequence on protein sequence harboring relevant genes, in which we highlighted the BOLA-DQB, BOLA-DQA5, CD1A, ?-defensins, PRG3, and ULBP21 genes. Enrichment analysis based on the gene list retrieved from the CNVRs disclosed over-represented terms (p?<?0.01) strongly associated with immunity and cattle resilience to harsh environments. Additionally, QTL associated with body conformation and dairy-related traits were also unveiled within the CNVRs. These results provide better understanding of the selective forces shaping the genome of such cattle breeds and identify traces of natural selection pressures by which these populations have been exposed to challenging environmental conditions. 650 $aBovino 650 $aGado Crioulo 650 $aGenoma 650 $aRaça 653 $aVariação fenotípica 700 1 $aSTAFUZZA, N. B. 700 1 $aMACHADO, M. A. 700 1 $aPANETTO, J. C. do C. 700 1 $aEGITO, A. A. do 700 1 $aBALDI, F. 700 1 $aSILVA, M. V. G. B. 773 $tAnimal Genetics$gv. 54, n. 3, p. 254-270, 2023.
Download
Esconder MarcMostrar Marc Completo |
Registro original: |
Embrapa Gado de Leite (CNPGL) |
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
Nenhum registro encontrado para a expressão de busca informada. |
|
|